In the future, a strange fungus has changed nearly everyone into a thoughtless, flesh-eating monster. When a scientist and a teacher find a girl who seems to be immune to the fungus, they all begin a journey to save humanity.
In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats. When the creatures escape from the briefcase, it sends the American wizarding authorities after Newt, and threatens to strain even further the state of magical and non-magical relations.
